Quality System Certified ISO 9001 AMO Magnetic Mixer High Speed Rev.2.doc Page 1 of 3 The AerreInox magnetic mixer high speed are designed complying with FDA rules for pharmaceutical and biotechnology industries. The most obvious advantage of the magnetic mixer is that enables the total integrity of the tank. The vessel shell is not penetrated and there are no mechanical seals or stuffing boxes; this minimized crosscontamination risk and also prevent toxic or high value media from leaking out of the vessel and thereby challenge the sterility of the vessel and its contents. Suitable for viscosities up to 800 cps the AerreInox AMO-Magnetic Mixer High Speed offers great flexibility. Bottom mounting also leaves the top of the vessel clear for easy vessel access. PRINCIPLE OF OPERATION The AerreInox Magnetic Mixer High Speed has a driven mixer that can be removed quickly and easily. A major advantage when sterilizing the vessel in an autoclave or when sharing a single drive units mechanism between vessels. A machined pad is welded into the bottom of the vessel (usually offset from a central bottom outlet valve). The impeller head is running by a drive unit mounts externally. Machined directly from a solid raw bar, inside the impeller head there is a ring of special magnets encapsulated in AISI 316L stainless steel housing. The stator come, also, in unique piece from a round bar. PERFORMANCE The geometry of the impeller allows an excellent axial pumping flow and very low shear rate for different applications, especially for Homogenizing that mean to transport one phase or ingredient (liquid, solid, gas) into a main continuous phase (typically liquid), with which it would normally be insoluble; - EMULSIFYING: the process of dispersing one liquid into a second insoluble liquid, such as oil dispersed in water. Producing a small droplet size is necessary in order to achieve a stable emulsion. - DISSOLVING or down sizing applications, dissolving is dispersing an insoluble or semi insoluble solid into a liquid. Down sizing is often desired to reduce the particle size of the solids to obtain a stable suspension. - SUSPENDING is dispersing of solid particles into a liquid. MAIN FEATURES - speed range 500 to 3000 rpm using an inverter, depending on the size of vessel and impeller-head small volumes can be achieved; (looking from the top, impeller always must rotate clockwise). - all product contact part are made in 1.4404 or 1.4435; - all surfaces that come into contact with the product are easily cleaned in place; - aseptic design; - The impeller head runs on a special grade tungsten carbide that has been manufactured under controlled conditions to achieve the correct size, grain structure and hardness. • The mixing capacities above are based on aqueous like products with a density of 1.000 Kg/m3 and a viscosity of 1cp. • AMO High Speed Mixer can also be combined with a standard AMT mixer to achieve a variety of powerful results, such as collapsing vortex to prevent foaming, increased agitation, maintained suspensions at low levels etc... Aerre Inox s.r.l. 26010 FIESCO Via Gerola n.4 -CREMONA - Italy Tel. +39. 0374. 370828 Fax +39. 0374. 370833 e-mail : [email protected] http : www.aerreinox.it

Quality System Certified ISO 9001 AMO Magnetic Mixer High Speed Rev.2.doc Page 2 of 3 Weld plate dimensions Surface roughness: Ra<0,5 micron or better, manually polished or manually polished + electro polished Material: stainless steel AISI 316L- 1.4404 or 1.4435 for round bar and blade plates, static female and dinamic male bearings in tungsten Carbide In Compliance with: the weld plate is classified in Europe, for PED Directive 97/23/EC Category IV and approved by Notified Body Non-standard executions available on request: Welding plate with bigger different thikness, shaft extension...

Quality System Certified ISO 9001 AMO Magnetic Mixer High Speed Rev.2.doc Page 3 of 3 Weld plate Impeller Static bearing Dinamic bearing Disk / O-Ring MATERIAL WETTED PARTS stainless steel AISI 316L- 1.4404 or 1.4435 stainless steel AISI 316L- 1.4404 or 1.4435 Tungsten Carbide Tungsten Carbide FDA and USP Class VI Number of poles 2 except Atex execution which have 4 poles Protection index IP 55 Certified CE/cCSAus, IEC, CEI/UNEL WELD PLATE Surface roughness design pressure design temperaure in compliance with Ra<0,5 micron or better manually polished or manually polished + electro polished -1...