SB50-X OrbShake
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SB50-X (OrbShake) Orbital shaken bioreactor for disposable bags

2 ᕡ Disposable bag with pH & DO sensors and various ports The SB50-X is an orbital shaken bioreactor for the cultivation of human, mammalian and plant cells in a disposable bag. A working volume from 15 litres up to 50 litres for the SB50-X ensures easy scale-up from microtiter plates to shaking flasks and all the way up to 200 litres. The SB50-X can be used in research, process development or production. Performance characteristics + Large capacity (50L working volume) + + + + single use bioreactor system Cultivation of human, mammalian and plant cells Fast, simple set up Easy scale-up...

ᕢ Reader Box-X: Online measurement of pH and DO SB50-X (OrbShake) | 3 ᕣ Filter heater Trouble free scale-up The SB50-X fills a gap in the scale-up chain from microtiter plates all the way up to 200 litres. The consistent hydro-dynamics of shaken bioreactors provide reproducible cultivation conditions throughout the volume range. The culture from the SB50-X can also serve as preculture or inoculum for the SB200-X. Control unit and online measurement The bespoke control unit, designed by Kuhner, uses the latest touch-screen technology and ISIS-X 8.0 software for data recording, calibration,...

Technical data Shaken bioreactor • Order number Shaker speed Shaker diameter Weight approx. 340 kg without liquid Active brake adjustable Cooling cooling coils are incorporated cooling system (pressure <0.2bar) • Mains connection Capacity 2 exhaust filters Temperature range Ambient temperature up to 70°C, Oxygen Sensor Opt'ca' measuring method pH Sensor Opt'ca' measuring method Accuracy ± 0.05 pH at pH 7 with one point calibration

Control unit with touchscreen monitor, ISIS-Software, pumps & gas mixing device • Order number Weight 15’’ touchscreen monitor for monitoring, calibration, controlling O2, pH, shaking speed, temperature one point recalibration is possible 21 CFR Part 11 compliance (audit trail) Maximum Speed Maximum Speed Delivery Pressure Delivery Pressure Flow rates (ml/min at 100rpm) Flow rates (ml/min at 100rpm)

Mixing up to four gases Gas mixtures can also be connected Number of mass flow controllers 4 Input up to 4 gases, push in connector [6 mm] (air, oxygen, nitrogen, carbon dioxide) (gas mixtures can also be connected) Output 1, (tube fitting for tube ID 13 [mm]) Flow rate 0 - 20 [sL/min] Accuracy ±1.5% from the end value Pressure sensor integrated, 0-400 [mbar], programmable prevents over pressure in the connected vessel prevents blocking the mass flow controllers Back pressure valve integrated, prevents reflux into the mass flow controllers Controlled filter heating box for the outlet...

SB50-X (OrbShake) | 7 ᕧ Tubing support bar Options Cooling The SB50-X has a cooling ring embedded in the base plate. Cooling is achieved by connecting an external cooling device. An integrated valve, controlled by the ISIS-Software, regulates the set point temperature. IQ-OQ Documentation IQ-OQ (Installation Qualification and Operation Qualification) is an equipment qualification required for GMP procedures. Documentation is available from Kuhner and Qualification services can also be provided at the customer`s premises. Tubing support bar ᕧ Order number: SMX714001 A tubing support bar is...

Shakers & Accessories www.kuhner.com Adolf Kühner AG • since 1949 Dinkelbergstrasse 1 CH – 4127 Birsfelden ( Basel ) Switzerland