The world's most reliable shaking machines Kuhner shaker • since 1949 Our motto: To build the world's most reliable shakers Kuhner AG is the leading developer and manufacturer of shaking machines for the international market. Founded in 1949 by Mr Adolf Kuhner, this family business is now led by his son Markus Kuhner. The «Kuhner shaker» name stands for functionality, reliability and durability. Kuhner guarantees its machines for 5 years, designing and building many components in-house. All processes are SN EN ISO 9001 certified. We endeavour to understand your science and cultivation needs to...

Shaking solutions for research and production Incubator Shakers Available with controlled CO2 & humidity Orbital shaken bioreactors (OSB) Orbital shaking Rack System Easy scale-up We have extended our product line. Visit our website to learn more about the Z-generation models. RC2-X

ShakerDrive Direct drive • Low energy consumption • Smooth running and quiet operation • Option of 3 direct drives: Standard, high speed, high power Changeable diameter Diameter can be adjusted by the user at any time T • hree standard shaking diameters: 12.5 mm, 25 mm and 50 mm O • ther shaking diameters are also possible: e.g. 70 mm for liquids with high viscosity • Option 3 mm/1000 rpm Parallelogram The parallelogram ensures identical shaking movement anywhere on the tray, regardless of load distribution. The double steel springs will last a lifetime. Only Kuhner can provide multiple shaking...

Foamed insulation The key to our precise KuhnerControl is the unique insulation process with CFC-free foam. Foaming is done by hand to ensure: • Precise control of process parameters • No condensation between insulation and casing • Reduced energy consumption • Silent operation Silent operation Temperature control Homogeneous temperature distribution across the entire shaking tray of a Kuhner incubator shaker ensures reproducible cultivation results. Precise temperature control with low energy consumption is guaranteed. Reliable control of CO2 is essential when working with mammalian or plant...

Interface Our wide range of interfaces keep you well connected Kuhner Insight Digital input Analogue output Alarm relay External Monitoring/ Alarm Kuhner insight For convenient supervision of the shaker with GMP features CAN-Ethernet Kuhner Insight Software Kuhner Insight is our user-friendly software for data recording, calibration, programming and controlling. Simultaneous recording of process parameters for up to 8 shakers is possible. Modbus/TCP Modbus/RTU DeviceNet profinet io PROFIBUS DP-V1 EtherNet/IP Delta V LabView OPC SCADA SPS/PLC Kuhner Insight Software

Temperature minimum ambient + 10 °C ambient - 15 °C (-10 °C) * ambient - 15 °C (-10 °C) * • Machine Gas volume 260 litre Weight (with cooling) 170 kg I Display / Interface Operating menu in Interface, standard Interface, optional © Temperature Setting, digital Accuracy, absolute (across the tray) Principle of sensor Power of heating Power of cooling Air circulation • Shaking unit Tray, size Loading, maximum Setting, digital Accuracy, absolute Timer Acceleration Active brake Stop on position ^ • Two units can be stacked without the need for special tools or stacking kits Shaking motion Speed *...

Technical data XC incubator shakers are optimised for cell cultivation     2 control option available: essential for CO mammalian, plant cell cultures and algae     Heated window and door frame with controlled humidity option User-friendly operation: each shaking     unit and parameter has its own control     Controlled humidity option: essential for cultivation in microtiter plates or when cultivating in flasks for long periods    Touchscreen option available • Overview SMX1600 / SMX1600C * SMX1601 / SMX1601C * SMX1603 / SMX1603C * Cooling no yes yes Humidity control no no yes Temperature minimum...

XC incubator shakers are optimised for cell cultivation • Overview Cooling Humidity control Temperature minimum CO2 control option available: essential for mammalian, plant cell cultures and algae Heated window and door frame with controlled humidity option Temperature maximum Humidity maximum Power consumption User-friendly operation: each parameter has its own control • Machine Gas volume 395 litre Weight (with cooling) 210 kg Controlled humidity option: essential for cultivation in microtiter plates or when cultivating in flasks for long periods Retrofitting possible * can be changed / other...

EcoDew®-Technology The newly developed EcoDew®-Technology provides precise humidity control without requiring a cooling-compressor-unit. The system was developed especially for customers using higher temperatures (10 °C above room temperature) and humidity, e.g. cell culture cultivations in general or cultivations in microtiter plates. Orbital shaken bioreactors (OSB) Scale-up without compromising quality     EcoDew® option available for ISF1-Z and LT-X EcoDew® condensation body F • or use in research, process development and production C • ultivation of human, mammalian, plant and insect cells...

• Overview Shaker speed Technical data subject to change ORBITAL SHAKEN BIOREACTORS (OSB) 20 • 21

Knowledge transfer Shaker Laboratory Kuhner AG offers advice on cultivations in shaken bioreactors. Our in-house laboratory uses a number of online-measuring methods and computer based models to support our customers. Collaboration with universities, especially with academic partners Prof. Büchs (AVT, RWTH Aachen, Germany) and Prof. em. Wurm (LBTC, EPFL Lausanne, Switzerland), can also provide answers to complex questions. This consultation service is confidential of course and free of charge for Kuhner customers. Seminars and Trainings Furthermore, Kuhner carries out seminars which address questions...