AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary
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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 1

AB SCIEX QTRAP ® 5500 SYSTEM Above and beyond the extraordinary AB SCIEX QTRAP ® 5500 SYSTEM

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 2

Powerful synergy results when the world's most sensitive triple quadrupole unites with innovative Linear Accelerator™ trap technology, the world's most sensitive and fastest scanning linear ion trap. The whole really is more than the sum of its parts. The unique hybrid architecture, unparalleled sensitivity, and impressive speed enable solution-based workflows that solve problems other mass spectrometry systems cannot. The QTRAP® 5500 system is truly above and beyond the extraordinary, with no sacrifice in qualitative or quantitative performance, whether targeting specific compounds or...

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 3

Above and beyond the extraordinary The AB SCIEX QTRAP® 5500 System is next-generation technology from the leaders in mass spectrometry. Redesigned from the ground up, but bred from our industry standard triple quadrupole line of mass spectrometers, the QTRAP 5500 System brings in a new era of performance. Fast, precise quantitative performance Ultra-fast triple quadrupole scan speeds improve precursor ion and neutral loss scan performance, ideal for fast chromatography. Fast LC also demands incredibly short dwell times for MRM experiments Let the innovative Scheduled MRM™ algorithm...

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 4

Many mass spectrometry systems offer either quantitative or qualitative structural analysis. But the unique hybrid architecture of the QTRAP® system means that you can get both exceptional qualitative and quantitative information from the same instrument and in the same analytical run. The unparalleled scan speeds and sensitivity of the QTRAP 5500 System are made possible by advanced eQ™ electronics. Next- generation eQ electronics in turn drive the unique TripleTrap™ scanning technology to move from triple quadrupole mode to Linear Accelerator™ trap mode in the blink of an eye, enabling...

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 5

The power of TripleTrap™ scanning is illustrated in the above metabolite ID example. In this UHPLC experiment, two survey scans for characteristic GSH fragments, a positive ion neutral loss of m/z 129 and a negative ion precursor ion scan of m/z 272, automatically trigger enhanced product ion scans to screen for potential reactive metabolites. Including the polarity switch between survey scans, the total cycle time is 2.1 seconds. M7 (3.50) 1.1e4 1.0e4 S/N=10 9.0e3 8.0e3 Intensity, cps 7.0e3 6.0e3 O 5.0e3 4.0e3 O 3.0e3 2.0e3 N 1.0e3 0.0e0 2.5 3.0 3.5 4.0 3e7 4.5 4.09 2.5e7 Intensity, cps...

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 6

Cutting edge technology and reliable too Due to our long legacy as the industry leader, our customers expect maximum uptime and a system that can handle even the most difficult matrices with ease. Our Turbo V™ source and Curtain Gas™ interface are the benchmark for reliability. The new QJet® ion guide, eQ™ electronics, Qurved LINAC collision cell, and AcQuRate™ pulse counting detector found in the QTRAP® 5500 System have been designed to improve on our already industry-leading robustness. With reliability designed into the system, new levels of dependability and consistency are certain....

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 7

Turbo V™ source provides high- sensitivity analysis over a wide range of flow rates with quick-change APCI and TurbolonSpray® probes. From 50 uL/min to 5 mL/min, the Turbo V source is the perfect match for narrow bore, standard bore and UHPLC flow rates, delivering unprecedented desolvation and stability for even the toughest high-flow applications utilized to drive productivity QJet® ion guide's patented design yields improved ion containment and operates at high pressure, providing better collisiona focusing to enhance ion transmission for ultimate sensitivity. The new design also reduces...

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 8

e future path of QTRAP® technology The AB SCIEX QTRAP® 5500 System brings together the latest hardware from the world's best selling triple quadrupole family, and adds next-generation, ultra-fast and sensitive Linear Accelerator™ trap functionality. Delivering unmatched qualitative and quantitative analysis—t QTRAP 5500 System enables productive, time-saving workflows that simply cannot be done with other mass spectrometry systems. AcQuRate™ Pulse Counting Detector The AcQuRate™ pulse counting detector is the latest in detector technology combined with a pulse overlap correction algorithm,...

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 9

Patented Linear Accelerator™ Trap Bringing LINAC® technology to the Q3 linear ion trap greatly improves the extraction efficiency to yield up to a 100 x gain in sensitivity in ion trap scan modes. Now take full advantage of the 20,000 Da/s scan speeds without worrying if enough sensitivity is on board to generate incomparable results. Improved excitation efficiencies and reduced ion cooling and fragmentation times produce superior MS3 gualitative results and provide unprecedented selectivity for the most challenging analytical assays. Patented Qurved LINAC® Collision Cell The newly designed...

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 10

Powerful, workflow-driven software ties everything together to deliver a new benchmark in efficiency, throughput, and productivity to let you take full advantage of all the speed and power that the QTRAP® 5500 System puts at your fingertips. And the latest version of industry-standard Analyst® software utilizes the intelligent Scheduled MRM™ algorithm to make the method setup of over 1000 analytes in a single LC analysis straightforward and simple while still generating exceptional quantitative results and brilliant qualitative results. ONE TOUCH PRODUCTIVITY SOLUTIONS MultiQuant™ Software...

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AB SCIEX QTRAP® 5500 System: Above and Beyond the Extraordinary - 11

"We designed the QTRAP® 5500 System from the ground up in response to customer feed- back on ideal attributes from a quantitative and qualitative point of view. Researchers wanted to combine these two elements to solve problems and save time and money. " DR. JIM HAGER, PRINCIPAL RESEARCH SCIENTIST LightSight® Software LightSight® Software simplifies analysis of complete metabolite coverage. Create expert-level acquisition methods in just a few simple steps using the automated method development tool or take advantage of the customized Glutathione screening ability that quickly identifies...

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