Cascade:128+ - Photometrics - #1

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H I G H - P E R F O R M A N C E E M C C D & C C D C A M E R A S F O R L I F E S C I E N C E S Primary applications Neurosciences Single-molecule fluorescence Live-cell microscopy Spinning-disc confocal microscopy 128 x 128 imaging array 24 x 24-ìm pixels Features Benefits EM gain Very high sensitivity Low-noise, impact-ionization process Back-illuminated EMCCD Highest available quantum efficiency (>90% peak QE) 128 x 128 imaging array 24 x 24-ìm pixels Small array facilitates fast readout Good resolution 12-MHz readout Excellent for live-cell microscopy 16-bit digitization Wide dynamic range allows detection of bright and dim signals in the same image Frame-transfer EMCCD 100% duty cycle to collect continuous data No mechanical shutter required Thermoelectric cooling Detector cooled to reduce background for high sensitivity C-mount Easily attaches to microscopes, standard lenses, or optical equipment Acquisition software Captures, analyzes, and saves high-resolution images PCI interface High-bandwidth, uninterrupted data transfer PVCAM® Circular buffers Device sequencing Supported by numerous third-party software packages Real-time focus Precise integration with shutters, filter wheels, etc. Compatible with Windows® XP/Vista 32, Mac OS X, and Linux® (kernel versions 2.4 and 2.6.8) The Cascade:128+ camera from Photometrics® uses a high-QE, back-illuminated CCD with EM gain to provide extraordinary sensitivity for low-light-level, live-cell microscopy applications. Its thermoelectrically cooled detection array features square, 24-ìm pixels in a 128 x 128, frame-transfer format. The state-of-the-art camera can collect more than 500 full frames of true 16-bit data per second — faster frame rates are achievable via subregion readout or binning. This unprecedented combination of speed and sensitivity makes the Cascade:128+ a perfect choice for neuroscience applications and single-molecule fluorescence (SMF) imaging.