Complete set of datasheets - optek-Danulat - #39

Single Channel NIR Absorption Probe inline control

Inline real time process monitoring

Concentration measurement insensitive to color changes

Superior sapphire window with no seals, gaps or crevices

Extremely low maintenance

CIP/SIP-compatible

Conforms to FDA requirements

The ASD25-N is a high-precision, single channel absorption probe. This stainless steel probe is engineered for use in pilot- or production scale fermenters or bioreactors. It precisely measures the growth of microbial or cell cultures as a function of NIR absorption. The extremely durable ASD25-N probe is designed for sanitary bioprocess environments and can be used in CIP/SIP processes.

The ASD25-N uses the light in the near infrared range (NIR) from 840 to 910 nm. A precisely defined and constant LED light beam penetrates the processamedium. The attenuation ofthe light intensity, caused by absorption and/or scattering by dissolved and undissolved substances, is detected by a hermetically sealed photo diode.

The ASD25-N probe is available with optical path lengths (OPL) of 1 mm, 5 mm, 10 mm or 20 mm. Shorter OPLs are typically used for dense cell cultures such as bacterial and yeast cultures. Longer OPLs are used for lower absorbing mammalian cell cultures. The probe performs concentration measurements insensitive to color changes, since an optical filter adapts the wavelength range.

The seal-less, sapphire optical window design eliminates crevices and gaps to assure the highest level of sterility, cleanability and sensor integrity. The surface ofthe wetted parts is electro-polished and may optionally comply with BN2. The probe mounts convenientlythrough a standard 25 mm Ingold-type port.

1 Opical path length (OPL) 4 Day-light filter

2 Sapphire windows 5 LED-light source

3 Detector

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