REVO ? SERIES Development Freeze-Dryer/ Lyophilizer
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Catalog excerpts

REVO ? SERIES Development Freeze-Dryer/ Lyophilizer - 1

THE REVO offers up to 10 sq ft of shelf area with a condensing rate of 20 Liters in 24 hours. It has the largest shelves and best shelf-to-shelf spacing of any system in its class, resulting in more product throughput in the same floor space. Using the best components and design techniques combined with the most advanced PC/PLC control system, offering data collection and self-testing features. THE REVO is the perfect solution for both your protocol development and small scale production needs. Our easy-to-use software provides automatic freeze-drying, defrost, system and leak rate testing. Data can be printed either numerically or graphically. This same control system is used on industrial dryers, allowing scaling to production. An interactive maintenance screen simplifies component servicing. All systems are remotely accessible, with customer approval, for trouble-shooting process issues. Advanced system options include FreezeBooster® Controlled Nucleation and Auto-Dry™ Protocol Optimization, AccuFlux™, and LyoPAT™ In-Process, Process Analytical Technology. The combination provides the ideal platform for simplified and optimized protocol development. THE REVO has been developed from over 50 years of experience in the freeze drying world. The standard system design provides a highly reliable platform for your freeze drying needs. Using more robust refrigeration components ensures the highest performance and reliability available. In addition, the system is designed to be more tolerant of fluctuations in room temperature and supply voltage, which are common issues with lower end systems. Unique design with features include: more accurate vacuum sensors; no rubber hoses; no vapor flow choke points; superior shelf temperature uniformity; reduced shelf temperature transition times; increased stoppering pressure; and more, to ensure that the equipment is not a limit to your freeze drying needs. REVO HIGHLIGHTS CONTROL SYSTEM • PC/PLC with ethernet and remote internet connectivity • Manual and automatic operating modes • Graphic and numeric data collection • Automatic System and Leak Rate Testing • Options for Protocol Optimization and Controlled Nucleation SHELF SYSTEM • Up to 10 sq. ft. of shelf area • Large shelves for more product capacity – 12" x 24" • Increased Stoppering Pressure – for 2ml vials • 316L on all wetted parts CONDENSER • 4" vapor port standard • Exposed coil condenser for maximum efficiency • Hot gas defrost REFRIGERATION • High reliability scroll compressors • Oversized refrigeration components for high reliability • CFC-Free, non-proprietary refrigerants VACUUM • Pirani vacuum sensor standard • Vacuum control standard • Gas backfill standard • 375LPM corrosion resistant vacuum pump OTHER • Sanitary style fittings on all sensor and vacuum ports • Built-in validation port – sanitary fitting SYSTEM PERFORMANCE • 5 Shelf pull down from +20 to –40C in less than 30 minutes • Vacuum pull down to 100 mT in less than 20 minutes • Vacuum leak rate less than 30 mT per hour REVO SERIES • Vacuum level 10 mT in clean dry system (-85) REVO™ SERIES Development Freeze-Dryer/ Lyophilizer APPLICATIONS • Cycle Optimization • Formulation Development/Stability Studies • Tissue Bank • R&D / Small Scale Production • Diagnostics Well Plates • Vials • Bulk Applications / Trays

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REVO ? SERIES Development Freeze-Dryer/ Lyophilizer - 2

FEATURES & SPECIFICATIONS SHELF CONFIGURATION REVO™ STANDARD FEATURES SPACING (in/mm) SHELF AREA SHELF ASSEMBLY Bulk or Hydraulic Stoppering SHELF TEMPERATURE RANGE SHELF HEAT TRANSFER Hollow Fluid Filled SHELF SIZE/FINISH VAPOR PORT CONDENSER TEMP CONDENSER CAPACITY CONDENSING RATE CONDENSER STYLE Exposed Coil COMPRESSORS (SCROLL) PRODUCT SENSORS VACUUM PUMP VACUUM CONTROL Pirani w/ Solenoid & Needle Valve CONTROL SYSTEM PC/PLC with Opt-Dry Software AVAILABLE OPTIONS BULK FILL (LITERS) DEPTH OPTI-DRY® PC/PLC CONTROL • FreezeBooster® Controlled Nucleation* • Auto-Dry™ Protocol Development...

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