high sensitivity isothermal titration calorimeter (ITC) - MicroCal LCC - #1

Isothermal Titration Calorimetry (ITC) is the gold standard for measuring biomolecular interactions. ITC directly provides a full thermodynamic profile elucidating the mechanism of the interaction -information that cannot be obtained from any other method.

The MicroCal VP-ITC system is the most sensitive isothermal titration calorimeter available. Designed for ease-of-use, all functions are operated through software to facilitate fast and accurate analyses, without the need for expertise in thermodynamics.

Applications include: characterization of molecular interactions of proteins, antibodies, nucleic acids, lipids and other biomolecules; lead optimization, enzyme kinetics and the assessment of the effect of molecular structure changes on binding mechanisms.

MicroCal instruments are found at major pharmaceutical, biotech, academic and government institutions worldwide.

binding affinities: True affinity data via heat

offers a unique insight into the biology processes, unobtainable with more assays.

versatility: Investigate any biomolecular

technique: No immobilization or required. No molecular weight limitations or restrictions. Easily handles turbid solutions.

Unattended operation after sample

system: No additional accessories to

No reagents or consumables are required.

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