Bohle-Innovativ-2011 - 12 Pages

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Catalogue excerpts

Bohle expands   location for   handling machines Start of construction in Sassenberg Dear Readers, 2010 was a very difficult year for Bohle, as it was for the entire industry. At the beginning of the year we had to institute reduced working hours. We were not sure whether we would be able to maintain current work force or if we would have to make lay-offs. Together with our staff the decision was made to not take the easy road and lay-off employees, but rather to cultivate the experience and dedication of our employees developed over many years. We focused on our innovative potential and the expected...

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L.B. Bohle at the Interpack From 12 to 18 May 2011 L.B. Bohle will be presenting a broad range of innovations and developments at the Interpack in Düsseldorf. One of the highlights to be presented on the 230 m trade fair booth, is the new Bohle Conti Granulator BCG, a synchronous, twinscrew extruder with a downstream dryer. The granulator will be presented along with a tablet press and the semi-continuous KOCO coater. The Bohle product range on show 2 for the attendees will also include the Film Coater BFC 5, the new Fluid Bed System BFS 3, the Bohle Turbo Sieve BTS, the Containment System BCK...

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Strong growth stimuli from the USA L.B. Bohle at the Interphex The economic upturn in the American pharmaceutical market is clearly noticeable. From 29 to 31 March the Interphex 2011 took place in the Jacob K. Javits Convention Center in New York. Over 650 exhibitors presented their new products and developments for the pharmaceutical industry. The American L.B. Bohle LLC subsidiary from Warminster, Pennsylvania, presented the new BFS 3 Fluid Bed System designed for lab applications at the trade fair. The Bohle team also introduced the innovative BCG granulator and the KOCO coater, capable of...

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Premium quality for customers in the pharmaceutical industry Interview with Andreas Altmeyer regarding Bohle's semi-continuous film coater KOCO® Mr. Altmeyer, Bohle initially focused on continuous processing. Today you are presenting the KOCO® coater as a semi-continuous production machine. Why? For some years now we have been dealing with the issue of continuous pharmaceutical processing. We have already introduced a number of fully continuous granulation systems. In this segment we currently have our model BCG, a continuous twin-screw extruder with a downstream contact dryer. However, trials...

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More solid despite less liquid Prof. Klaus-Jürgen Steffens of Bonn University has tested the new extruder Professor, you have already carried out a number of tests with the BCG (Bohle Conti Granulator). Please explain to us the basic operation method of the system. The core of the system is a newly designed GMP-compliant twin-screw extruder, which is supplied by a continuous mass-controlled powder dosing unit and a continuous liquid dosing unit. The finished granulate falls directly into the continuous rotating vacuum contact dryer, without requiring transport. The dryer operates with an innovative...

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mixture which must first be dissolved in the extruder. We actually expected significant problems with the tablet strength, as HPMC 4000 has a much lower dissolution rate in water than PVP. Specimens A to F were granulated with different screw configurations and different amounts of liquid. Only specimen E showed a significant capping tendency of the tablets. This specimen was produced with the least amount of liquid. Despite having virtually the same strengths, in the range of 2.5 MPa, the tablets from the other specimens revealed varying disintegration times, ranging from 133 sec (specimen F)...

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“Flexibility is decisive” Interview with Dr. Michael Beyer Wiewelhove GmbH, a contract manufacturer for the pharmaceutical industry based in Ibbenbüren, has the first Compact Unit in operation.“Innovativ” interviewed Dr. Michael Beyer, Director of Production and Engineering at Wiewelhove, on the application range and benefits of the compact unit. Dr. Beyer, please explain to us which applications you use the new system for. Until recently we mainly used tray drying for new projects including drying processes as the existing fluid bed system was operating at near full capacity. However, we wanted...

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Did you plan to manufacture a specific product with the new system? No, there were no particular specifications. For Wiewelhove – as a contract manufacturer – it is of paramount importance that a broad range of products can be manufactured with our systems allowing us to flexibly respond to our customers’ requirements. Finally, can you describe your first experiences with the new system? We installed the system in our production facilities in 2010. After completing all qualification protocols, extensive tests with the compact unit were carried out. These tests revealed excellent results in the...

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After its founding in 1989, the Pratteln-based Swiss company Konapharma initially focused on preparing dossiers for pharmaceutical customers. Since 1995, the company has also become a contract manufacturer for the pharmaceutical industry. In 2009, the company relocated to a new, 6000 sqm facility and now employs around 100 staff and has firmly established itself on the market as a manufacturer of solid dosage forms. "Innovativ" interviewed Dr. Thomas Koy, Production Manager, about his experience with Bohle products. Dr. Koy, which Bohle systems do you use and how long have you been using them? Several...

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Publisher: L.B. Bohle Maschinen + Verfahren GmbH IndustriestraGe 18 59320 Ennigerloh Germany Tel.: +49 2524 9323-0 Fax: +49 2524 9323-29 E-Mail: Internet: Layout & Print:

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