PR-23-AC - 6 Pages

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Catalogue excerpts


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TYPICAL APPLICATIONS PHARMACEUTICAL CHEMICALS Acetylsalicylic acid, Calcium gluconate, Glycerophosphates, Chloral hydrate, Saccharin, Antihistamines, Tranquilizers, Antifilarials, Diethyl carbamazine citrate, Antidiabetics and more. ACTIVE PHARMACEUTICAL INGREDIENTS Actives, Excipients, Intermediates, Raw material, Fine chemicals, and Bulk chemicals. Penicillin, Streptomycin, Tetracyclines, Chloramphenicol, and Antifungals. BLOOD PRODUCTS Blood, Plasma, Serum, Infusion liquids, Sodium chloride, and Glucose. Proteins and Protein buffer solutions SYNTHETIC DRUGS Sulfa drugs, Antituberculosis drugs,...

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REGULATORY COMPLIANCE Food and Drug Administration's (FDA's) regulations require documented act of demonstrating that a specific procedure, process, and activity will consistently lead to the expected results. This is called validation. K-Patents Process Refractometer PR-23 is ideal real-time instrument that meets the pharmaceutical industry standards and guidelines including PAT, GMP CIP/ , SIP 21 CFR Part 11 and validation. The , ability to understand and continuously control parameters such as Refractive Index nD contributes significantly to the development of effective drugs and efficient...

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DIGITAL MEASUREMENT PRINCIPLE Optical image Light source Critical angle Process medium The light source sends light against the interface between a prism and the process solution, where the rays meet the surface at different angles. Prism Reflected light Light source The angle corresponding to the shadow line is called the Critical Angle of Total Reflection. The Critical Angle is a function of the refractive index and therefore the con­­ tration of the solution. cen­ Refracted light Depending on the angle, some rays are totally reflected. And, some rays are only partially reflected, most of the...

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DESIGN Air cooling fins Processor card Thermal conductor Thermal isolation CCD-camera Light source Prism Temperature sensor CORE-Optics All measuring components (light source, prism, temperature sensor and CCD-camera) are in one solid CORE-optics module. The patented CORE-optics is mechanically isolated from the influence of external forces and vibrations. The CORE-optics contains no mechanical adjustments. (US Patent No. 6067151)

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SPECIFICATIONS Compact sensor PR-23-AC: Refractive Index range: Automatic, digital compensation According to ISO 9000 quality system: NIST traceable with standard R.I. liquids and Transmitter's menu guided procedure and report for printing Ambient temperature: Built-in Pt-1000, linearization according to IEC 751 Instrument verification: Light emitting diode (LED), 589 nm wavelength, sodium D-line Temperature compensation: Light source: Temperature sensor: No mechanical adjustments (US Patent No. US6067151) Digital measurement: With Cargille standard R.I. liquids over full range of nD 1.3200...1.5300 Laboratory...

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