Group: HORIBA
Catalog excerpts
Multiplex Label-Free Interaction Analysis Only Limited By Your Imagination
Open the catalog to page 1Multiplex Label-Free Molecular In Accelerate your research and maximize your workflow with XelPleX combines the power of multiplexing (measuring multiple interactions simultaneously) and the sensitivity of Surface Plasmon Resonance, resulting high-resolution kinetic profiles. The revolutionary fluidics system and the integrated autosampler are compatible with a broad range of applications, such as ligand fishing in complex fluids, cell studies, small molecule detection, and protein and DNA analysis. Driven by the EzSuite software platform, XelPleX is simple to operate and is designed to...
Open the catalog to page 2nteraction Platform Instant information from real time display of images Binding events are followed in real time on the kinetic curves and also on the SPRi difference image. White spots on this image correspond to areas where binding has occurred – giving you a clear Yes/No answer to molecule detection and recognition. Biochip image before interaction Biochip SPRi difference image after interaction Cell Science Optimized fluidics system Drug Discovery and Development Working with complex samples like serum, plasma or cell lysates, in diagnostic research or drug discovery, is not an issue....
Open the catalog to page 3Expand your Research Palette Instant affinity profiling using a single-injection step The single-injection step takes advantage of multiplexing by determining the affinity of analytes binding to different ligands using only one analyte concentration injection (no regeneration step required) - saving you time and samples. Direct comparison of wild-type (WT) and Mutant single-chain variable fragments (scFv) Optimization of immobilization concentratior Small molecules detection made easy The revolutionary optical and fluidics units obtain unsurpassed performance for high-sensitivity...
Open the catalog to page 4nd compare for the best using only one sensor chip Rank and screen your molecules during selection processes t immobilization concentrations, n the same sensor chip, and optimize al conditions of your interaction s many replicate spots as you wish to ent in the results. Multiplexing helps you to rank and screen molecules such as antibodies or aptamers according to affinity or kinetic rates easily and rapidly. Thanks to the SPRi-CFM printer, molecules can be immobilized from crude media to be compatible with your bioprocessing workflow. n and pH on the binding response of a small otein...
Open the catalog to page 5High-Performance Multiplexed Label-Free In n EzView software retrieves real time information through flow cell and SPRi difference images, and kinetics status. hundred ligands can be monitored simultaneously. as many negative controls as you wish. Accurate real time referencing brings more confidence to your results. Make decisions faster with instant information display Snapshot of the EzView control software Snapshot of the autosampler settings in EzView sequences can be programmed in the EzView software to automatically control the integrated autosampler. the running solution form up to...
Open the catalog to page 6nteraction Instrument n Simply load your experiment data from the database, and perform your analysis in a few clicks. Collect and report data in a flash with EzAnalysis retrieves quantitative information and performs data quality control automatically. reporting of the experimental details (buffer, flow rate, temperature…), and of the analysis, to keep records of all your experiments. Quantitative analysis with EzAnalysis Data clouding of a 300 peptides array for epitope mapping (based on Scrubber) cleans and fits kinetics data to a 1:1 interaction model to calculate affinity and kinetic...
Open the catalog to page 7Discover the Label-Free Platform from HORIBA Scientific This document is not contractually binding under any circumstances - Printed in France - ©HORIBA Jobin Yvon 02/2015 www.horiba.com/scientific info.sci@horiba.com
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