Rapid separation systems high-end performance
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Rapid separation systems   high-end performance - 1

Thermo Scientific Dionex UltiMate 3000 RSLC Systems Rapid separation systems high-end performance Speed • Resolution • Versatility

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Rapid separation LC accelerate your analysis The Thermo Scientific Dionex UltiMate 3000 Rapid Separation LC (RSLC) systems accelerate HPLC for unrivaled performance and flexibility. Precision-engineered instrumentation, advanced data processing, and highly optimized chemistries meet all chromatographic performance challenges. With its binary, quaternary, and dual-gradient pumps, these industry-leading systems offer versatility covering the maximum range of HPLC, including conventional and ultrafast LC. Together, these characteristics make RSLC the only available choice for highest...

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The Right Combination of Components and Data Management The UltiMate 3000 RS systems deliver superior performance, excelling at pressures of 100 MPa (15,000 psi) and flow rates up to 8 mL/min. Detector and autosampler technologies, powerful software, and small particle columns contribute to RSLC capabilities. Solution Component Binary, Quaternary, or Dual Gradient RS Pump Pressure up to 100 MPa (15,000 psi) at flow rates up to 8 mL/min In-line Split Loop Well Plate Sampler Cycle times of 15 s Injection volumes of up to 500 µL Thermostatted RS Column Compartment Temperature range of 5–110 °C...

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Ingredients for speed exceptional application range A Complete Package for Performance Leadership 10 µm particles 5 µm particles 3 µm particles 2.2 µm particles H [µm] Engineered to the highest level of performance, the UltiMate 3000 RS systems deliver the key flow rate and pressure capabilities to meet all LC challenges. With its extensive flow-pressure footprint, short sampler cycle times, high column temperatures, ultrafast data collection and processing, and high-resolution columns, the system maximizes LC flexibility. This combination of features delivers optimal separations at...

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High Flow and Efficiency UltiMate 3000 RS systems are designed to deliver robust operation at high flow rates and high pressure. • Backpressures up to 100 MPa (15,000 psi) RSLC Provides Unrivaled Speed: 10 Peaks in 10 Seconds • Flow rates up to 8 mL/min • Oven temperatures up to 110 °C • Data collection rates up to 200 Hz Separation of uracil and nine alkylphenones in 10 s, with a full 100 Hz DAD spectral scan. The run was performed using a flow rate of 3.7 mL/min, a backpressure of 730 bar, an oven temperature of 100 °C, and a 30 × 2.1 mm C18 column with 1.8 µm particle size. Benzoate...

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High-resolution RSLC boost speed and productivity Resolution and Speed: Meeting the Challenge for Superior LC Achieving the highest resolution in the fastest run times takes more than a great LC system. High resolution also requires low extracolumn volumes and long columns with small particle sizes. Achieve highresolution UHPLC by improving efficiency and reduceing band broadening. Small particle sizes significantly increase efficiency; lower extracolumn volumes ensure that this increase is not lost again due to band broadening. Reducing particle size increases separation of compounds,...

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Small Particle Size Columns Provide the Highest Efficiency To optimize your fast separations, the UltiMate 3000 RS systems deliver the lowest extracolumn volumes and highest efficiency with small particle size columns. 16 • Dedicated range of 1, 2.1, and 3 mm i.d. high-resolution columns • Revolutionary Viper fingertight fitting system for performance without compromise • Comprehensive mixer portfolio from 35 µL to 1550 µL for a wide application range • Unique, easily scalable Thermo Scientific SpinFlow mixer technology • Compatible with all commercially available stationary phases...

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Beyond UHPLC unique solutions UHPLC Reaches a New Level of Flexibility and Performance UltiMate 3000 ×2 Dual RS systems offer laboratories unprecedented sample throughput and easy automation of advanced procedures. Seamless integration of UHPLC with ×2 Dual RSLC technology and powerful Chromeleon software brings laboratories new possibilities: • Doubled sample throughput with parallel and tandem LC • Increased use time by automatically switching between applications • Highest selectivity and resolution with multidimensional LC The DGP-3600RS combines two UHPLC pumps in a single housing....

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Connect to the Future The revolutionary Viper fitting system does away with all problems experienced with conventional fitting systems. It provides a perfect fit each time it is used and ensures superior chromatographic performance. • Straightforward, zero-dead-volume UHPLC fingertight fittings • Compatible with virtually every type of valve and column hardware • Tool-free, Viper-based kits for advanced LC solutions All RSLC tubing kits and UHPLC+ solutions feature the unique Viper design, making the best UHPLC system even easier to use. Slipping capillaries cause deteriorated peak shapes...

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Instant results seamless integration Chromeleon Software Ensures that RSLC is Ultrafast All UHPLC+ systems and solutions are powered by Chromeleon Chromatography Data System software that produces results instantly The following features ensure increased productivity and a laboratory focus on results, not just data, • Data processing times reduced by as much as 90% • Instant calculation of results • Integrated method transfer wizard for quick and easy conversion of conventional LC methods to RSLC methods • Dedicated reports for method validation, related substances, EPA statistics,...

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Acetylsalicylic acid RSLC Data Processing UHPLC requires ultrafast data handling. Chromeleon software delivers seamless data handling that ensures instant results. Dissolution Profile Using a fast dissolution method with a total run time of 18 s allows the analysis of all dissolution samples in less than 30 min. After that, the dynamic processing tools of the Chromeleon software instantly calculate the dissolution profile and assess the results against specifications. From sample to results in fewer Using Chromeleon software, a 40 page validation report (based on ICH guidelines) is created...

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