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Chromatograph, Autosampler, Sampler, Thermal desorber, Gas chromatograph
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ITSP or Instrument Top Sample Prep for
Serial Solid Phase Extraction and Sample Filtration
Offers True Increases In Productivity
The concept is so simple. We use an autosampler syringe as the
reservoir of a SPE column, or the disposable syringe for a cartridge
filter. We use the needle of the syringe to maintain a vertical position of
the device so that it can be moved by the instrument anywhere on the
instrument’s platform. By piercing a septum attached to the top of the
needle guide, the analytical syringe can pressurize the needle guide to
pass a fluid across bedmass chemistry or the preferred membrane for
filtration. Depending on the preference of the researcher and the
application, it can flow fluid in either direction.
Each Sample Is Self-Contained For Increased
Efficiency and Productivity
Each sample is self-contained so mistakes can be realized before an
entire group of samples has been processed. Likewise, chemistries can
be checked and chain of custody can be maintained from sample to
sample. Even instrument failures do not result in a loss of more than
one sample as each one is prepped and sampled before the next
sample begins the same process.
While it sounds intensive to serial prep samples, realistically the
only downtime is that of the first sample. In many instances, the
analytical instrument takes longer to run the prepped sample than it
takes to actually prep the sample.
There is no need for an expensive liquid handler or a cumbersome
and inconsistent vacuum manifold device as ITSP is performed on
the LC or GC by the CTC Analytics PAL Sample Handler with a minimum
amount of modification. Many instruments only need the ITSP Hardware
Start-Up Kit.
96-well SPE Microplates Offer Users
Only a Fraction of ITSP Capability
Method developers always want to test solvent strengths and matrixes
to optimize their desired extraction and minimize solvent usage.
Sometimes multiple fractions are the desired and 96-well based
extractions just can’t offer these options without much interaction of
the researcher. Further, one mistake can ruin all of your samples. While
liquid handlers offer individual column capabilities, it is not uncommon
to have to scale a method up rather than down. Liquid handlers also
require a transfer by the researcher to the analytical instrument. Small
bedmass volumes combined with ITSP movement offer many advantages
over current product offerings.
With ITSP each sample is run individually so you can check your
work in progress and make adjustments so that no loss of sample
occurs. Pressurizing multiple wells is eliminated so there is no loss of
samples or inconsistency of extraction due to leaks or loss of vacuum.
Introducing ITSP™
Instrument Top Sample Prep
TOP 10 FINALIST FOR
BEST NEW
PRODUCT
AT ASSOCIATION OF
LAB AUTOMATION 2007
ITSP is protected under the following US Patents 6,859,615 & 7,001,774. Canadian Patent 2,316,648. Foreign Patents Pending.
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